(A) Bacteriocins downregulate the expression of the BCl-2 gene, upregulate the BAX gene, and induce mitochondria to release Cyt c which activates the intrinsic pathway resulting in apoptosis.
(B) EPS binds to the TLR and activates c-Jun which helps in the activation of the caspase-8-mediated extrinsic apoptotic pathway.
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